Does the research focus on the cell biological (including neuronal) abnormalities found in LS?
Would the research outcomes most directly align with the LSA’s research goal to identify targets amenable to the development of meaningful treatment (or treatments- drug, therapy, etc.) for LS by 2030?
Does the research focus on cognitive or kidney involvement or both in LS?
Does the research have implications for diseases other than LS and therefore may have greater overall impact in the research community?
Do the research findings provide cell lines or other data or materials for other researchers to use and is there a plan for disseminating these data or materials?
Has the researcher identified and/or requested additional sources of funding to share the research cost or is willing to seek additional sources of funding?
Does the proposal include a detailed budget, timelines and anticipated outcomes?
Does the proposal include provisions for a summary report 2 months before the end of the funding period and 6 months after the start of the project?
The Lowe Syndrome Association, Inc., (LSA) is an international, voluntary, non-profit
organization made up of parents, professionals, and others who are interested in Lowe syndrome. It was founded in 1982 and incorporated in 1986.
The primary purposes of the LSA are to: foster communication among families, promote a better understanding of Lowe syndrome and the potentials of individuals with this condition, provide information, and encourage and support medical research relating to Lowe syndrome. The LSA publishes a biannual newsletter, On the Beam, online content, communicates via Facebook and other social media outlets and sponsors international conferences. The official slogan of the LSA is “Circle of Care…Vision for a Cure.”
The LSA, is governed by a Board of Directors. In scientific and medical issues, the Board solicits the advice of the LSA Medical and Scientific Advisory Board, which is made up of physicians and scientists representing various backgrounds.
The LSA is prepared to provide annual funds to support an appropriate research project. The researcher may re-apply for a second year of funding, if offered.
The LSA invites applications from researchers of all types, including but not limited to universities, hospitals, and other non-profit organizations with interest in research in the previously specified areas.
The LSA grant money may not be used as salary for the principal investigator, for honoraria for consultants, for the purchase of standard, non-consumable laboratory equipment, to purchase services from other research laboratories, or for overhead or indirect costs. Also, grant funds must be held in interest-bearing accounts payable to the grant.
The researcher must submit a progress report at the end of six months for annual grants. This report must include a financial statement showing the expenditure of grant funds. Consideration for re-application for a subsequent grant will depend on satisfactory progress demonstrated in the progress report. A final report must be submitted after twelve months and all unexpended funds must be returned to the LSA.
If any human subjects are involved in research supported by the LSA, the researcher must obtain the informed consent of each subject, or the informed consent of a parent or guardian for each minor subject, prior to the participation of human subjects in any study or procedure.
No research involving human subjects shall be made unless the research is given initial and continuing review and approval by an appropriate committee of the researcher’s institution. The institution must provide written assurance that the research project complies with the regulations of the United States Department of Health and Human Services (see IV.A.10 below).
The total application must be no more than 12 pages (8″ x 11″) long, not including
curriculum vitae and bibliography. Each application must contain the following items:
Proposals can be submitted via the submission form above or email before the deadline to: Jeri Kubicki, VP, Lowe Syndrome Association at firstname.lastname@example.org.